We chose to have a 2:1:1 ratio of leucine, isoleucine, and valine because it's been shown in research to be the most effective. It was shown that leucine had a better effect on protein synthesis, but they’ve also found that increased levels of leucine by itself doesn’t yield that much extra results. Taking leucine alone vs taking it with the 2:1:1 ratio with the other 2 BCAAs has been shown to have less effective results. The short answer as to why this happens is that our muscles naturally contain a 2:1:1 ratio of leucine to valine to isoleucine.
There are A LOT of supplement companies that claim that a higher BCAA ratio than 2:1:1 is far more beneficial, but this is not true. Dosing higher levels of any of these BCAAs outside of the 2:1:1 ratio will likely deplete the other two BCAAs as valine has cognitive benefits and isoleucine has fat burning benefits. Any ratio higher than this is a marketing gimmick and a complete waste of money. Our 2:1:1 ratio BCAA Tablets are formulated with a 2:1:1 ratio of leucine to isoleucine and valine. Boost your protein synthesis into overdrive and get back in the gym faster.
Here are all 3 branched chain amino acids:
Leucine (1,500 mg / serving), Isoleucine (750 mg / serving), Valine (750 mg / serving)
The general recommended dose if BCAAs is 20g/day of combined leucine, valine, and isoleucine. The dose should also be a 2:1:1 ratio of leucine (2-10g) and valine/isoleucine (48-72mg per kg or bodyweight) per day. To maximize the benefits of your BCAA tablets, at a minimum, take 3 tablets before your workout. For maximum results, take 3 additional tablets after your workout.
The tolerable upper limit of BCAAs is 35g/day of BCAAs, so you don’t want to consume more than this. Taking this much wouldn’t’ be effective anyway, and would be a waste of money. You don’t need to cycle BCAAs on/off, therefore you can take them every day to help maximize your results. You can also take BCAAs on an empty stomach or with food. The best time of the day to take BCAAs is around your workouts, half of the portion of the daily limit pre-workout and the other portion post-workout.
There's no need to cycle on/off BCAAs so feel free to take it every day.
Some companies decide to market BCAAs products separately for women and men, however this is just a gimmick – BCAAs work the same for men and women. The dose should depend on a person’s total body weight, overall goals, etc. However, there is not enough reliable information about the safety of taking branched-chain amino acids if you are pregnant or breast feeding. Stay on the safe side and avoid use.
BCAA supplements have been on the market for decades, and many years of research on BCAAs has studied the effects on metabolism, neurology, physical performance, and interactions with medical condition.
BCAAs are completely safe to take, but the tolerable upper limit of BCAAs is 35g/day.
There aren’t many known side effects of taking BCAAs for the general population. However, consuming them as a supplement could interact with some medical conditions. It is always a good idea to speak with your healthcare provider before starting any supplement regimen.
Branched-chain amino acids might affect blood sugar levels, and this might interfere with blood sugar control during and after surgery. Stop using branched-chain amino acids at least 2 weeks before a scheduled surgery.